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Article

A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID‐activated gene

27 Feb 2009

Abstract excerpt

Astragalus membranaceus has been used to ameliorate the side effects of antineoplastic drugs because of its immunomodulating nature. We had recently demonstrated that total Astragalus saponins (AST) possess anticarcinogenic and proapoptotic properties in human colon cancer cells and tumor xenograft. In this study, we identified NSAID-activated gene (NAG-1) as a potential molecular target of AST. The...

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Share to Cancer, Lipids, and Metabolism
Share to Inflammatory mediators and NSAID effects
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PMID: 19384947
DOI: 10.1002/ijc.24397

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