Arg-Gly-Asp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts.

doi:10.1016/0014-4827(91)90386-9

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Article

Arg-Gly-Asp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts.

Experimental cell research - 1 Aug 1991

Horton M A, Taylor M L, Arnett T R, Helfrich M H

Abstract excerpt

Studies with a range of monoclonal and polyclonal antisera to components of the human, rat, and chick vitronectin receptor, alpha V beta 3, and the VLA beta 1 chain show that chick and rat osteoclasts express similar integrin receptors to those described in man. Biochemical analysis with monoclon...

Topics

Amino Acid Sequence
Animals
Animals, Newborn
Antibodies
Antibodies, Monoclonal
Bone Resorption
Cell Movement
Chickens
Dentin
Humans
Integrins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligopeptides

Osteoclasts

Phenotype

Rats

Receptors, Immunologic

Receptors, Vitronectin

Source

Open in PubMed

Identifiers

PMID: 1712731
DOI: 10.1016/0014-4827(91)90386-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1712731-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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