Article
Endothelial nitric oxide synthase gene polymorphisms and the risk of acute myocardial infarction in a South Indian population.
Molecular biology reports - 1 Feb 2013
Arun Kumar Annan Sudarsan, Umamaheswaran Gurusamy, Padmapriya Ramamoorthy, Balachandar Jayaraman, Adithan Chandrasekaran
Abstract excerpt
Myocardial infarction (MI) is a complex multi-factorial, polygenic disorder which results from an interaction between a person's genetic makeup and various environmental factors. Nitric oxide (NO), a potent vasodilator produced by endothelial cells, plays an important role in the regulation of blood pressure, regional blood flow and also inhibits platelet aggregation, vascular smooth muscle cell proliferation and...
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