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Article

Evolutionary history of Salmonella typhi.

Science (New York, N.Y.) - 24 Nov 2006

Roumagnac Philippe, Weill François-Xavier, Dolecek Christiane, Baker Stephen, Brisse Sylvain, Chinh Nguyen Tran, Le Thi Anh Hong, Acosta Camilo J, Farrar Jeremy, Dougan Gordon, Achtman Mark

Abstract excerpt

For microbial pathogens, phylogeographic differentiation seems to be relatively common. However, the neutral population structure of Salmonella enterica serovar Typhi reflects the continued existence of ubiquitous haplotypes over millennia. In contrast, clinical use of fluoroquinolones has yielded at least 15 independent gyrA mutations within a decade and stimulated clonal expansion of haplotype H58 in Asia and...

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PMID: 17124322
DOI: 10.1126/science.1134933
PMCID: PMC2652035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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