The origins of haplotype 58 (H58) Salmonella enterica serovar Typhi

Abstract excerpt

<title>Abstract</title> <p>Antimicrobial resistance (AMR) poses a serious threat to the clinical management of typhoid fever. AMR in <italic>Salmonella</italic> Typhi (<italic>S</italic>. Typhi) is commonly associated with the H58 lineage, a lineage that arose comparatively recently before becoming globally disseminated. To better understand when and how H58 emerged and became dominant, we performed detailed phyl...

Topics

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• Anti-Bacterial Agents
• Drug Resistance, Multiple, Bacterial
• Genome, Bacterial
• Haplotypes
• Mutation
• Phylogeny
• Salmonella typhi
• Typhoid Fever

Identifiers and source

Literature Corpus work

00181d44-41e6-56dd-816d-70da7b8748d8

DOI

10.21203/rs.3.rs-4183920/v1