Article
Short report: Severe Plasmodium falciparum malaria in Cameroon: associated with the glutathione S-transferase M1 null genotype.
The American journal of tropical medicine and hygiene - 1 Nov 2006
Kavishe Reginald A, Koenderink Jan B, McCall Matthew B B, Peters Wilbert H M, Mulder Bert, Hermsen Cornelus C, Sauerwein Robert W, Russel Frans G M, Van der Ven Andre J A M
Abstract excerpt
Glutathione S-transferases (GST) are a family of enzymes involved in phase-II detoxification of endogenous and xenobiotic compounds. Polymorphisms in GST genes have been associated with susceptibility to different diseases. In this study we determined the frequencies of polymorphisms in GSTM1, GSTT1, and GSTP1 in DNA of 138 children from Cameroon, presenting with uncomplicated malaria (N = 19), malaria with minor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
