Article
A single-nucleotide synonymous mutation in the gag gene controlling human immunodeficiency virus type 1 virion production.
Journal of virology - 1 Feb 2007
Hamano Takaichi, Matsuo Kazuhiro, Hibi Yurina, Victoriano Ann Florence B, Takahashi Naoko, Mabuchi Yosio, Soji Tsuyoshi, Irie Shinji, Sawanpanyalert Pathom, Yanai Hideki, Hara Takashi, Yamazaki Shudo, Yamamoto Naoki, Okamoto Takashi
Abstract excerpt
Viral factors as well as host ones play major roles in the disease progression of human immunodeficiency virus type 1 (HIV-1) infection. We have examined cytotoxic T-lymphocyte activity and HIV-1 DNA PCR results of 312 high-risk seronegative drug users in northern Thailand and identified four seronegative cases positive for both assays. Furthermore, we have identified a synonymous mutation in nucleotide position...
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