Article
Evidence for a prostate cancer linkage to chromosome 20 in 159 hereditary prostate cancer families.
Human genetics - 1 May 2001
Zheng S L, Xu J, Isaacs S D, Wiley K, Chang B, Bleecker E R, Walsh P C, Trent J M, Meyers D A, Isaacs W B
Abstract excerpt
Prostate cancer is the most common malignancy diagnosed in men in the US. Genetic susceptibility to prostate cancer has been well documented. A region at chromosome 20q13 (HPC20) has been reported to be linked to a prostate cancer susceptibility gene. To confirm this finding, we genotyped 16 markers spanning approximately 95 cM on chromosome 20 in 159 hereditary prostate cancer (HPC) families. Positive (but not...
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