Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibrinogen-beta gene haplotype is associated with mortality in sepsis.

The Journal of infection - 1 Jun 2007

Manocha Sanjay, Russell James A, Sutherland Ainsley M, Wattanathum Anan, Walley Keith R

Abstract excerpt

OBJECTIVES: Fibrinogen plays a key role in coagulation and inflammation. Transcription of the fibrinogen-beta gene (FGB) is the rate-limiting step in fibrinogen production. Our aim was to determine whether haplotypes of FGB are associated with mortality and organ dysfunction in a cohort of patients with sepsis. METHODS: A prospective cohort of 631 consecutive Caucasian patients with sepsis from a tertiary care...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Chi-Square Distribution
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrinogen

Share to Gene Frequency

Share to Haplotypes

Share to Outcome Assessment, Health Care

Share to Sepsis

Source

Identifiers

PMID: 17116333
DOI: 10.1016/j.jinf.2006.10.001

Genes

GAA
FGB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibrinogen-beta gene haplotype is associated with mortality in sepsis.PMID 17116333Read ↗

A genome-wide association study of survival in patients with sepsis.Semantic proximity Read ↗

Tumor necrosis factor -308 polymorphism (rs1800629) is associated with mortality and ventilator duration in 1057 Caucasian patients.Semantic proximity Read ↗

Genomic polymorphisms in sepsisSemantic proximity Read ↗

Issues with polymorphism analysis in sepsis.Semantic proximity Read ↗

The association of interleukin 6 haplotype clades with mortality in critically ill adults.Semantic proximity Read ↗

Common genetic polymorphisms and haplotypes of fibrinogen alpha, beta, and gamma chains affect fibrinogen levels and the response to proinflammatory stimulation in myocardial infarction survivors: the AIRGENE study.Semantic proximity Read ↗

The effect of four hemostatic gene polymorphisms on the outcome of septic critically ill patients.Semantic proximity Read ↗

A common haplotype of the LBP gene predisposes to severe sepsis.Semantic proximity Read ↗

IRAK1 functional genetic variant affects severity of septic shock.Semantic proximity Read ↗

Protein C -1641 AA is associated with decreased survival and more organ dysfunction in severe sepsis.Semantic proximity Read ↗

Coagulation Phenotypes in Sepsis and Effects of Recombinant Human Thrombomodulin: An Analysis of Three Multicenter Observational StudiesSemantic proximity Read ↗

Protein C -1641A/-1654C haplotype is associated with organ dysfunction and the fatal outcome of severe sepsis in Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.