Article
TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects.
Human genetics - 1 Mar 2007
Carlson Christopher S, Heagerty Patrick J, Nord Alex S, Pritchard David K, Ranchalis Jane, Boguch Joshua M, Duan Hangjun, Hatsukami Thomas S, Schwartz Stephen M, Rieder Mark J, Nickerson Deborah A, Jarvik Gail P
Abstract excerpt
Inflammatory markers have consistently been associated with vascular disease. Evidence of genetic polymorphisms in inflammatory loci that predict severe carotid artery disease (CAAD) would suggest that this relationship is not secondary to other correlated factors, but related to inflammation itself. We examined the full common genetic variation in 42 inflammatory loci for prediction of severe CAAD versus...
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