Genome-Wide Association Study Identifies Human Genetic Variants Associated with Systemic Chronic Inflammation.

Abstract excerpt

Chronic low-grade inflammation has been identified as the etiology of disease across the life span; however, the underlying genetic mechanism are poorly understood, and no genetic association study is performed. Here, we quantified chronic low-grade inflammation using the low-grade inflammation score (INFLA-score) and performed a genome-wide association study in a large European cohort of 217,984 individuals,...

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• Apolipoproteins E
• Chronic Disease
• APOE gene
• Genetic Predisposition to Disease
• Genome-Wide Association Study