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Genetic correlation and causal associations between circulating C-reactive protein levels and lung cancer risk.

Cancer causes & control : CCC - 1 Jun 2024

Shi Jiajun, Wen Wanqing, Long Jirong, Xue Haoran, Yang Yaohua, Tao Ran, Pan Wei, Shu Xiao-Ou, Cai Qiuyin

Abstract excerpt

PURPOSE: We aimed to characterize genetic correlations and causal associations between circulating C-reactive protein (CRP) levels and the risk of lung cancer (LC). METHODS: Leveraging summary statistics from genome-wide association studies of circulating CRP levels among 575,531 individuals of European ancestry, and LC risk among 29,266 cases and 56,450 controls, we investigated genetic associations of...

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PMID: 38332239
DOI: 10.1007/s10552-024-01855-7

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