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Circulating C-reactive protein increases lung cancer risk: Results from a prospective cohort of UK Biobank.

International journal of cancer - 1 Jan 2022

Ji Mengmeng, Du Lingbin, Ma Zhimin, Xie Junxing, Huang Yanqian, Wei Xiaoxia, Jiang Xiangxiang, Xu Jing, Yin Rong, Wang Yuzhuo, Dai Juncheng, Jin Guangfu, Xu Lin, Zhu Chen, Hu Zhibin, Ma Hongxia, Zhu Meng, Shen Hongbing

Abstract excerpt

Chronic inflammation has been associated with the development of lung cancer. In this study, we examined the association between C-reactive protein (CRP) and lung cancer in a prospective cohort study and used Mendelian randomization (MR) to clarify the causality. We included 420 977 participants from the UK Biobank (UKB) in the analyses; 1892 thereof were diagnosed with lung cancer during the follow-up. Hazards...

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Identifiers

PMID: 34449869
DOI: 10.1002/ijc.33780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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