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Strategies to Modulate Immune Responses: A New Frontier for Gene Therapy

7 Jul 2009

Abstract excerpt

The success of gene therapy strategies to cure disease relies on the control of unwanted immune responses to transgene products, genetically modified cells and/or to the vector. Effective treatment of an established immune response is much harder to achieve than prevention of a response before it has had a chance to develop. However, preventive strategies are not always effective in avoiding immune responses,...

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PMID: 19584819
DOI: 10.1038/mt.2009.150

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