Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Borrelia burgdorferi basic membrane proteins A and B participate in the genesis of Lyme arthritis.

The Journal of experimental medicine - 21 Jan 2008

Pal Utpal, Wang Penghua, Bao Fukai, Yang Xiuli, Samanta Swapna, Schoen Robert, Wormser Gary P, Schwartz Ira, Fikrig Erol

Abstract excerpt

Lyme arthritis results from colonization of joints by Borrelia burgdorferi and the ensuing host response. Using gene array-based differential analysis of B. burgdorferi gene expression and quantitative reverse trancription-polymerase chain reaction, we identified two paralogous spirochete genes, bmpA and bmpB, that are preferentially up-regulated in mouse joints compared with other organs. Transfer of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Borrelia burgdorferi
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Complementation Test

Share to Inflammation

Share to Lyme Disease

Share to Mice, Inbred C3H

Share to Open Reading Frames

Source

Open in PubMed Open full text

Identifiers

PMID: 18166585
DOI: 10.1084/jem.20070962
PMCID: PMC2234379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Borrelia burgdorferi basic membrane proteins A and B participate in the genesis of Lyme arthritis.PMID 18166585Read ↗

Single-cell RNA sequencing of murine ankle joints over time reveals distinct transcriptional changes following Borrelia burgdorferi infectionSemantic proximity Read ↗

Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis modelSemantic proximity Read ↗

Lyme Disease PathogenesisSemantic proximity Read ↗

Gene Expression Profiling Reveals Unique Pathways Associated with Differential Severity of Lyme ArthritisSemantic proximity Read ↗

Tick-specific borrelial antigens appear to be upregulated in American but not European patients with Lyme arthritis, a late manifestation of Lyme borreliosis.Semantic proximity Read ↗

BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts.Semantic proximity Read ↗

In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in MiceSemantic proximity Read ↗

Temporal Expression Analysis of the Borrelia burgdorferi Paralogous Gene Family 54 Genes BBA64, BBA65, and BBA66 during Persistent Infection in MiceSemantic proximity Read ↗

Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production.Semantic proximity Read ↗

Analysis of the bmp gene family in Borrelia burgdorferi sensu lato.Semantic proximity Read ↗

Comparative transcriptome analysis of Peromyscus leucopus and C3H mice infected with the Lyme disease pathogenSemantic proximity Read ↗

MyD88 plays a unique role in host defense but not arthritis development in Lyme disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.