Article
Expression of blood dendritic cell antigens (BDCAs) by CD1a+ human pulmonary cells.
Respiratory medicine - 1 Jun 2009
Tsoumakidou Maria, Kemp Sarah J, Thorley Andrew J, Zhu Jie, Dewar Ann, Jeffery Peter K, Tetley Teresa D
Abstract excerpt
BACKGROUND: Myeloid and plasmacytoid dendritic cell (DC) subsets have been recently identified in the human lung based on their differential expression of Blood DC Antigens 1-3 (BDCAs). We investigated the expression of these antigens by isolated human pulmonary CD1a(+) DCs, namely Langerhan's cells. METHODS: Using an in vitro cell culture system we successfully isolated a population of relatively pure (>70%)...
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