Article
Characterization of CD56+ dendritic-like cells: a normal counterpart of blastic plasmacytoid dendritic cell neoplasm?
PloS one - 1 Jan 2013
Osaki Yohei, Yokohama Akihiko, Saito Akio, Tahara Kenichi, Yanagisawa Kunio, Ogawa Yoshiyuki, Ishizaki Takuma, Mitsui Takeki, Koiso Hiromi, Takizawa Makiko, Uchiumi Hideki, Saitoh Takayuki, Handa Hiroshi, Murakami Hirokazu, Tsukamoto Norifumi, Nojima Yoshihisa
Abstract excerpt
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy. Plasmacytoid DCs (pDCs), which are defined as lineage marker (Lin)(-)HLA-DR(+)CD56(-)CD123(+)CD11c(-) cells, are considered to be the normal counterpart of BPDCNs. However, BPDCN can be distinguished from pDCs by uniform expression of CD56. In this study, to identify a normal counterpart of BPDCN, we searched for a...
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