Article
A startling role for synaptic zinc.
Neuron - 22 Nov 2006
Kay Alan R, Neyton Jacques, Paoletti Pierre
Abstract excerpt
It has long been known that the synaptic vesicles of certain glutamatergic terminals, as well as some inhibitory terminals, are richly supplied with zinc ions, yet the functional role of this pool of zinc in synaptic transmission has remained elusive. In this issue of Neuron, Hirzel et al. provide direct in vivo evidence that endogenous zinc is required for proper functioning of neuronal circuitry in the...
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