Article
CHO glycosylation mutants: GPI anchor.
Methods in enzymology - 1 Jan 2006
Maeda Yusuke, Ashida Hisashi, Kinoshita Taroh
Abstract excerpt
Glycosylphosphatidylinositol (GPI) is used for anchoring many cell surface proteins to the plasma membrane. Biosynthesis of GPI anchor, its attachment to proteins, and modification of GPI-anchored proteins (GPI-APs) en route to the plasma membrane are complex processes (Ferguson, 1999; Kinoshita and Inoue, 2000). GPI-AP-defective mutant cell lines derived from CHO and other cells have been very useful in...
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