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Article

High anxiety and migraine are associated with the s allele of the 5HTTLPR gene polymorphism.

Psychiatry research - 15 Jan 2007

Gonda Xenia, Rihmer Zoltan, Juhasz Gabriella, Zsombok Terezia, Bagdy Gyorgy

Abstract excerpt

The 5HTTLPR polymorphism of the serotonin transporter gene has been associated with anxiety disorders and also migraine, suggesting a common etiological background of these disorders. This association is further supported by the high comorbidity of these disorders. In our study Spielberger's State-Trait Anxiety Inventory and the 5HTTLPR genotype were investigated in a cohort of 97 psychiatrically healthy females...

Topics

Adult
Alleles
Anxiety Disorders
DNA Primers
Female
Gene Expression
Genotype
Humans
Male
Migraine Disorders
Phenotype
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serotonin Plasma Membrane Transport Proteins

Severity of Illness Index

Source

Identifiers

PMID: 17113652
DOI: 10.1016/j.psychres.2006.05.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17113652-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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