Article
Despite the general correlation of the serotonin transporter gene regulatory region polymorphism (5-HTTLPR) and platelet serotonin concentration, lower platelet serotonin concentration in migraine patients is independent of the 5-HTTLPR variants.
Neuroscience letters - 16 Oct 2003
Juhasz Gabriella, Zsombok Terezia, Laszik Andras, Jakus Rita, Faludi Gabor, Sotonyi Peter, Bagdy Gyorgy
Abstract excerpt
Platelet serotonin (5-HT) concentrations in a headache-free period during the mid-follicular phase and the serotonin transporter gene regulatory region polymorphism (5-HTTLPR) were measured in female migraine patients without aura (n = 64) and healthy controls (n = 42). High-pressure liquid chromatography (HPLC) was used to determine the platelet 5-HT concentration and genetic polymorphism was determined by...
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