Article
A polymorphism in the serotonin transporter gene regulatory region and frequency of migraine attacks.
Headache - 1 Oct 2002
Kotani Kazuhiko, Shimomura Tokio, Shimomura Fumiyo, Ikawa Shiro, Nanba Eiji
Abstract excerpt
BACKGROUND: The serotonergic system has been thought to play an important part in the pathophysiology of migraine. OBJECTIVE: To study an association between the polymorphism of serotonin (5-hydroxytryptamine [5-HT]) transporter gene-linked polymorphic region (5-HTTLPR) and migraine. Method.-We compared 151 patients with migraine with 190 healthy unrelated control subjects. The 5-HTTLPR polymorphism was detected...
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