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Article

The importance of MDR1 gene polymorphisms for tacrolimus dosage.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 15 Feb 2016

Kravljaca Milica, Perovic Vladimir, Pravica Vera, Brkovic Voin, Milinkovic Marija, Lausevic Mirjana, Naumovic Radomir

Abstract excerpt

Polymorphisms of the multi drug resistance (MDR1) gene cause variability in P-glycoprotein mediated metabolism of tacrolimus. The aim of this study was to examine the relationship between MDR1 gene single nucleotide polymorphisms (SNPs) and their haplotypes with dosage of tacrolimus in kidney transplant recipients who were cytochrome (CYP) 3A5*3 homozygotes. This study included 91 kidney transplant recipients...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26705892
DOI: 10.1016/j.ejps.2015.12.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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