Article
Effect of a rabeprazole half-dose twice daily on acid inhibition in patients with different CYP2C19 alleles.
European journal of clinical pharmacology - 1 Sept 2020
Murata Masaki, Sugimoto Mitsushige
Abstract excerpt
PURPOSE: Fractional doses of proton pump inhibitors (PPIs) more often than once daily (qd) inhibit 24-h acid secretion more effectively than an increase in the standard single daily dose. Although rabeprazole 5 mg qd is covered for prevention of aspirin-induced gastric injury under the Japanese insurance system, it is unclear whether rabeprazole 5 mg twice daily (bid) would more effectively inhibit acid...
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