Article
Implications for molecular mechanisms of glycoprotein hormone receptors using a new sequence-structure-function analysis resource.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 2007
Kleinau Gunnar, Brehm Mara, Wiedemann Urs, Labudde Dirk, Leser Ulf, Krause Gerd
Abstract excerpt
Comparison between wild-type and mutated glycoprotein hormone receptors (GPHRs), TSH receptor, FSH receptor, and LH-chorionic gonadotropin receptor is established to identify determinants involved in molecular activation mechanism. The basic aims of the current work are 1) the discrimination of r...
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