Article
N-linked glycosylation status of classical swine fever virus strain Brescia E2 glycoprotein influences virulence in swine.
Journal of virology - 1 Jan 2007
Risatti G R, Holinka L G, Fernandez Sainz I, Carrillo C, Lu Z, Borca M V
Abstract excerpt
E2 is one of the three envelope glycoproteins of classical swine fever virus (CSFV). Previous studies indicate that E2 is involved in several functions, including virus attachment and entry to target cells, production of antibodies, induction of protective immune response in swine, and virulence. Here, we have investigated the role of E2 glycosylation of the highly virulent CSFV strain Brescia in infection of the...
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