Article
ErbB2 overexpression in p53-inactivated mammary epithelial cells.
FEBS letters - 27 Nov 2006
Yang Jin Won, Lee Eva Y-H P, Kang Keon Wook
Abstract excerpt
Functional loss of p53 and ErbB2 overexpression are the frequent genetic alterations in human breast carcinomas. Here, we found that ErbB2 expression was upregulated in primary cultured mammary epithelial cells (MECs) isolated from mice with a defect in exons 5 and 6 of the p53 gene (p53(Delta5,6...
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