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Article

SCALEs: multiscale analysis of library enrichment.

Nature methods - 1 Jan 2007

Lynch Michael D, Warnecke Tanya, Gill Ryan T

Abstract excerpt

We report a genome-wide, multiscale approach to simultaneously measure the effect that the increased copy of each gene and/or operon has on a desired trait or phenotype. The method involves (i) growth selections on a mixture of several different plasmid-based genomic libraries of defined insert s...

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PMID: 17099705
DOI: 10.1038/nmeth946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17099705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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