One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY!

doi:10.1534/g3.116.037044

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Article

One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY!

G3 (Bethesda, Md.) - 5 Jan 2017

Herricks Thurston, Dilworth David J, Mast Fred D, Li Song, Smith Jennifer J, Ratushny Alexander V, Aitchison John D

Abstract excerpt

Cell growth is a complex phenotype widely used in systems biology to gauge the impact of genetic and environmental perturbations. Due to the magnitude of genome-wide studies, resolution is often sacrificed in favor of throughput, creating a demand for scalable, time-resolved, quantitative methods of growth assessment. We present ODELAY (One-cell Doubling Evaluation by Living Arrays of Yeast), an automated and...

Topics

Cell Cycle
Cell Proliferation
Gene-Environment Interaction
Genetic Heterogeneity
Genome, Fungal
Phenotype
Saccharomyces cerevisiae
Single-Cell Analysis
Systems Biology

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Identifiers

PMID: 27856698
DOI: 10.1534/g3.116.037044
PMCID: PMC5217116

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