Article
Macrophage phenotype is associated with disease severity in preterm infants with chronic lung disease.
PloS one - 1 Jan 2014
Prince Lynne R, Maxwell Nicola C, Gill Sharonjit K, Dockrell David H, Sabroe Ian, McGreal Eamon P, Kotecha Sailesh, Whyte Moira K
Abstract excerpt
BACKGROUND: The etiology of persistent lung inflammation in preterm infants with chronic lung disease of prematurity (CLD) is poorly characterized, hampering efforts to stratify prognosis and treatment. Airway macrophages are important innate immune cells with roles in both the induction and resolution of tissue inflammation. OBJECTIVES: To investigate airway innate immune cellular phenotypes in preterm infants...
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