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Article

Role of tyrosine residues in modulation of claudin-4 by the C-terminal fragment of Clostridium perfringens enterotoxin.

Biochemical pharmacology - 15 Jan 2007

Harada Motoki, Kondoh Masuo, Ebihara Chiaki, Takahashi Azusa, Komiya Eriko, Fujii Makiko, Mizuguchi Hiroyuki, Tsunoda Shin-Ichi, Horiguchi Yasuhiko, Yagi Kiyohito, Watanabe Yoshiteru

Abstract excerpt

The C-terminal fragment of Clostridium perfringens enterotoxin (C-CPE) modulates the barrier function of claudin-4 via its C-terminal 16 amino acids. In the current study, we investigated the roles of tyrosine residues (Y306, Y310 and Y312) in this region in the modulation of TJs by C-CPE. Single...

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Identifiers

PMID: 17097620
DOI: 10.1016/j.bcp.2006.10.002

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CPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17097620-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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