Article
[Application of denaturing high performance liquid chromatography to mutation detection of the c-kit gene in mastocytosis].
Zhongguo shi yan xue ye xue za zhi - 1 Oct 2006
Zhang Ling-Yan, Xu Gong-Li, Cross Nicholas C P
Abstract excerpt
The aim of study was to detect mutation of tyrosine domain of c-kit gene in mastocytosis using denaturing high performance liquid chromatography technique, and to investigate the significance of this gene mutation in diagnosis and therapy of mastocytosis. Genomic DNA was obtained from bone marrow...
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