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Article

[The application of denaturing high performance liquid chromatography in detection of novel polymorphisms in PAI-1gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2003

Wang Xu-dong, Fu Yan, Jiang Hui-jie, Morisaki Hiroko, Morisaki Takayuki

Abstract excerpt

OBJECTIVE: To detect single nucleotide polymorphisms(SNPs) in codon region of plasminogen activator inhibitor-1 (PAI-1) gene and associate them with development of coronary artery disease(CAD). METHODS: Denaturing high performance liquid chromatography(DHPLC) and DNA sequencing were used to scan all of exons in PAI-1 gene in 93 CAD patients and 123 control subjects. RESULTS: Two polymorphisms in exon 2, G43A and...

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PMID: 14556193

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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