Article
Expression profiling of MAP kinase-mediated meiotic progression in Caenorhabditis elegans.
PLoS genetics - 10 Nov 2006
Leacock Stefanie W, Reinke Valerie
Abstract excerpt
The LET-60 (Ras)/LIN-45 (Raf)/MPK-1 (MAP kinase) signaling pathway plays a key role in the development of multiple tissues in Caenorhabditis elegans. For the most part, the identities of the downstream genes that act as the ultimate effectors of MPK-1 signaling have remained elusive. A unique allele of mpk-1, ga111, displays a reversible, temperature-sensitive, tissue-specific defect in progression through...
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