Article
A mouse monoclonal antibody specific for an allotypic determinant of the Igha allele of murine IgM: genetic and functional analysis of Igh-6a epitopes using anti-IgM monoclonal antibodies.
Hybridoma - 1 Feb 1991
Sieckmann D G, Stall A M, Subbarao B
Abstract excerpt
An IgG1 mouse monoclonal antibody (MAb) specific for a mouse IgM allotypic determinant in the a, c, f, g, h, and j haplotypes was derived from a fusion of SP2/O-Ag14 mouse myeloma cells with C57BL/6 mouse spleen cells (Igh-Cb) immune to TC31, a MAb of the IgMa allotype. MAb from one hybridoma der...
Topics
- Alleles
- Animals
- Antibodies, Anti-Idiotypic
- Antibodies, Monoclonal
- Antibody Specificity
- B-Lymphocytes
- Epitopes
- Genes, Immunoglobulin
- Hybridomas
- Immunoglobulin Allotypes
- Immunoglobulin Heavy Chains
- Immunoglobulin M
- Lymphocyte Activation
- Mice
- Mice, Inbred Strains