Comparison of CH1 domains in different classes of murine antibodies.

doi:10.1006/jmbi.1996.0582

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Article

Comparison of CH1 domains in different classes of murine antibodies.

Journal of molecular biology - 1 Nov 1996

Sheriff S, Jeffrey P D, Bajorath J

Abstract excerpt

The CH1 domains of antibodies belonging to the following five murine immunoglobulin (Ig) classes IgG1, IgG2a, IgG2b, IgG3 and IgA have been compared. The IgG CH1 domain structures are, as would be expected, similar overall, but show local conformational variations. When compared with IgG CH1 doma...

Topics

Amino Acid Sequence
Animals
Immunoglobulin Constant Regions
Immunoglobulin alpha-Chains
Immunoglobulin gamma-Chains
Mice
Molecular Sequence Data
Mutation
Protein Structure, Tertiary
Sequence Alignment

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