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Article

The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice.

Journal of immunological methods - 15 Mar 1998

Martin R M, Brady J L, Lew A M

Abstract excerpt

Isotyping and quantitation of murine IgG2a antibodies are widely performed with commercial monoclonal and polyclonal antisera raised against BALB/c IgG2a myeloma proteins. Recently it became evident that inbred mouse strains with the Igh1-b allele do not have the gene for IgG2a and instead express the IgG2c isotype. We show that commercial anti-IgG2a sera cross-react inadequately against IgG2c in immunoblot and...

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Identifiers

PMID: 9672206
DOI: 10.1016/s0022-1759(98)00015-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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