Article
Apolipoprotein E polymorphism and preclinical carotid artery disease in untreated hypertensive men.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology - 1 Feb 2006
Bleil Maria E, Ferrell Robert E, Sutton-Tyrrell Kim, Muldoon Matthew F, Manuck Stephen B
Abstract excerpt
METHODS: The apolipoprotein E (apoE) polymorphism was evaluated alone, and in interaction with smoking status, in predicting carotid intima-medial thickness and plaque among 182 untreated, hypertensive, white men (mean age 56+/-8.9 years). RESULTS: After covariate adjustment (age, education, smoking, body mass index, systolic and diastolic blood pressure, glucose, total : high-density lipoprotein), apoE genotype...
Topics
- Adult
- Aged
- Apolipoproteins E
- Carotid Artery Diseases
- Genotype
- Humans
- Hypertension
- Logistic Models
- Male
- Middle Aged
- Multivariate Analysis
- Polymorphism, Genetic
- Smoking