Article
Gln27Glu variant of Beta2-adrenoceptor gene affects male type fat accumulation in women.
Lipids in health and disease - 15 Oct 2009
Kunnas Tarja, Lahtio Riikka, Kortelainen Marja-Leena, Kalela Anne, Nikkari Seppo T
Abstract excerpt
BACKGROUND: The beta2-adrenergic receptor (BAR2) is the main lipolytic receptor in white human adipose tissue. There is a functional glutamine 27 glutamic acid (Gln27Glu, rs 1042714) polymorphism in its gene, which has been variably associated with body mass index. This gene variant may be associated with male-type adiposity in women and thus increased cardiovascular risk. We investigated whether the BAR2...
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