Article
MDM2 T309G polymorphism is associated with bladder cancer.
Anticancer research - 1 Jan 2000
Onat Onur Emre, Tez Mesut, Ozçelik Tayfun, Törüner Gökçe A
Abstract excerpt
Recently, a functional T to G polymorphism at nucleotide 309 in the promoter region of the MDM2 gene (rs: 2279744, SNP 309) has been identified. This polymorphism has an impact on the expression of the MDM2 gene, which is a key negative regulator of the tumor suppressor molecule p53. The effect o...
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