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Article

Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants.

Biochemical and biophysical research communications - 29 Dec 2006

Lee Eun Hui, Song Dong-Woo, Lee Jae Man, Meissner Gerhard, Allen Paul D, Kim Do Han

Abstract excerpt

Triadin in the junctional sarcoplasmic reticulum (SR) of skeletal muscle cells has been suggested to interact with ryanodine receptor 1 (RYR1) via its KEKE motifs. Recently, we showed that amino acid residues D4878, D4907, and E4908 in RYR1 are critical for triadin-binding in vitro [J.M. Lee, S.H. Rho, D.W. Shin, C. Cho, W.J. Park, S.H. Eom, J. Ma, D.H. Kim, Negatively charged amino acids within the intraluminal...

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Source

Identifiers

PMID: 17092484
DOI: 10.1016/j.bbrc.2006.10.115

Genes

RYR1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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