Article
Increasing genetic relatedness of ciprofloxacin-resistant Streptococcus pneumoniae isolated in Canada from 1997 to 2005.
Antimicrobial agents and chemotherapy - 1 Mar 2008
Nichol Kimberly A, Adam Heather J, Karlowsky James A, Zhanel George G, Hoban Daryl J
Abstract excerpt
The genetic relatedness of ciprofloxacin-resistant Streptococcus pneumoniae isolates collected from 1997 to 2002 (n = 82) and 2003 to 2005 (n = 123) was compared by pulsed-field gel electrophoresis (PFGE). Increased genetic homogeneity among the isolates from 2003 to 2005 (cluster analysis; P < 0.001) appeared to be due to expansion of existing clonal groups and to introduction of new PFGE types.
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