Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Flavivirus Activation of Plasmacytoid Dendritic Cells Delineates Key Elements of TLR7 Signaling beyond Endosomal Recognition

1 Nov 2006

Abstract excerpt

TLR7 senses RNA in endosomal compartments. TLR7 expression and signaling have been demonstrated in plasmacytoid and myeloid dendritic cells, B cells, and T cells. The regulation of TLR7 signaling can play a crucial role in shaping the immune response to RNA viruses with different cellular tropisms, and in developing adjuvants capable of promoting balanced humoral and cell-mediated immunity. We used unique...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17082628
DOI: 10.4049/jimmunol.177.10.7114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Flavivirus Activation of Plasmacytoid Dendritic Cells Delineates Key Elements of TLR7 Signaling beyond Endosomal RecognitionPMID 17082628Read ↗

Cutting Edge: Antibody-Mediated TLR7-Dependent Recognition of Viral RNASemantic proximity Read ↗

Infection with the dengue RNA virus activates TLR9 signaling in human dendritic cellsSemantic proximity Read ↗

Differential TLR-ERK1/2 activity promotes viral ssRNA and dsRNA mimic-induced dysregulated immunity in macrophagesSemantic proximity Read ↗

Viral proteins recognized by different TLRsSemantic proximity Read ↗

SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8Semantic proximity Read ↗

RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?Semantic proximity Read ↗

Activation of the innate immune response by endogenous retrovirusesSemantic proximity Read ↗

TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infectionSemantic proximity Read ↗

Replication-independent activation of human plasmacytoid dendritic cells by the paramyxovirus SV5 Requires TLR7 and autophagy pathwaysSemantic proximity Read ↗

Detection of Microbial Infections Through Innate Immune Sensing of Nucleic AcidsSemantic proximity Read ↗

dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunitySemantic proximity Read ↗

Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.