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Article

Mapping the binding site of arginine vasopressin to V1a and V1b vasopressin receptors.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 2007

Rodrigo Jordi, Pena Ana, Murat Brigitte, Trueba Miguel, Durroux Thierry, Guillon Gilles, Rognan Didier

Abstract excerpt

Starting from the 2.8-A resolution x-ray structure of bovine rhodopsin, three-dimensional molecular models of the complexes between arginine vasopressin and two receptor subtypes (V1a, V1b) have been built. Amino acid sequence alignment and docking studies suggest that four key residues (1.35, 2.65, 4.61, and 5.35) fine tune the binding of vasopressin and related peptide agonists to both receptor subtypes. To...

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PMID: 17082326
DOI: 10.1210/me.2006-0202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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