Article
Association between the CHRM2 gene and intelligence in a sample of 304 Dutch families.
Genes, brain, and behavior - 1 Nov 2006
Gosso M F, van Belzen M, de Geus E J C, Polderman J C, Heutink P, Boomsma D I, Posthuma D
Abstract excerpt
The CHRM2 gene is thought to be involved in neuronal excitability, synaptic plasticity and feedback regulation of acetylcholine release and has previously been implicated in higher cognitive processing. In a sample of 667 individuals from 304 families, we genotyped three single-nucleotide polymorphisms (SNPs) in the CHRM2 gene on 7q31-35. From all individuals, standardized intelligence measures were available....
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