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Article

Exploring the functional role of the CHRM2 gene in human cognition: results from a dense genotyping and brain expression study.

BMC medical genetics - 8 Nov 2007

Gosso Florencia M, de Geus Eco J C, Polderman Tinca J C, Boomsma Dorret I, Posthuma Danielle, Heutink Peter

Abstract excerpt

BACKGROUND: The CHRM2 gene, located on the long arm of chromosome 7 (7q31-35), is involved in neuronal excitability, synaptic plasticity and feedback regulation of acetylcholine release, and has been implicated in higher cognitive processing. The aim of this study is the identification of functional (non)coding variants underlying cognitive phenotypic variation. METHODS: We previously reported an association...

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Identifiers

PMID: 17996044
DOI: 10.1186/1471-2350-8-66
PMCID: PMC2198911

Genes

CHRM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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