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Article

MGRN1 is linked to recessive heart and laterality defects: the first genotype-phenotype report in humans.

Journal of medical genetics - 25 May 2026

Kasak Laura, Rull Kristiina, Valkna Anu, Laan Maris

Abstract excerpt

Recurrent idiopathic severe fetal structural anomalies present major challenges for reproductive decision-making and genetic counselling. A non-consanguineous healthy Estonian couple had experienced two electively terminated pregnancies at 12-13 weeks' gestation due to unexplained major fetal malformations and one early miscarriage. Their three pregnancies had resulted in unaffected newborns. Exome sequencing of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41781207
DOI: 10.1136/jmg-2025-111380
PMCID: PMC13217038

Genes

MGRN1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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