Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of Cdc42-dependent signalling in Saccharomyces cerevisiae by phosphatase-dead SigD/SopB from Salmonella typhimurium.

Microbiology (Reading, England) - 1 Nov 2006

Rodríguez-Escudero Isabel, Rotger Rafael, Cid Víctor J, Molina María

Abstract excerpt

Heterologous expression of bacterial virulence factors in Saccharomyces cerevisiae is a feasible approach to study their molecular function. The authors have previously reported that the Salmonella typhimurium SigD protein, a phosphatidylinositol phosphatase involved in invasion of the host cell, inhibits yeast growth, presumably by depleting an essential pool of phosphatidylinositol 4,5-bisphosphate, and also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to cdc42 GTP-Binding Protein, Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle

Share to Cell Polarity

Share to Phosphoric Monoester Hydrolases

Share to Saccharomyces cerevisiae

Share to Sequence Alignment

Share to Signal Transduction

Source

Identifiers

PMID: 17074912
DOI: 10.1099/mic.0.29186-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of Cdc42-dependent signalling in Saccharomyces cerevisiae by phosphatase-dead SigD/SopB from Salmonella typhimurium.PMID 17074912Read ↗

The amino-terminal non-catalytic region of Salmonella typhimurium SigD affects actin organization in yeast and mammalian cells.Semantic proximity Read ↗

Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase.Semantic proximity Read ↗

A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol phosphatase activity and Akt activation.Semantic proximity Read ↗

Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P <sub>2</sub> by a phosphotransferaseSemantic proximity Read ↗

Killing of Candida albicans filaments by Salmonella enterica serovar Typhimurium is mediated by sopB effectors, parts of a type III secretion system.Semantic proximity Read ↗

RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42.Semantic proximity Read ↗

Yeast as a Heterologous Model System to Uncover Type III Effector Function.Semantic proximity Read ↗

Different domains of the essential GTPase Cdc42p required for growth and development of Saccharomyces cerevisiae.Semantic proximity Read ↗

Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P2 by a phosphotransferaseSemantic proximity Read ↗

SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34.Semantic proximity Read ↗

Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae.Semantic proximity Read ↗

Transcriptional activation upon pheromone stimulation mediated by a small domain of Saccharomyces cerevisiae Ste12p.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.