Article
Distribution of signal transducer and activator of transcription 6 gene G2964A polymorphism in Chinese patients with ulcerative colitis.
Journal of gastroenterology and hepatology - 1 Dec 2006
Zhu Jianbo, Xia Bing, Guo Qiusha, Cheng Hong, Li Jin, Ye Mei, Hu Zhengguo, Zhang Xiaolian, Tan Jingquan
Abstract excerpt
BACKGROUND AND AIMS: The signal transducer and activator of transcription 6 (STAT6) gene is located on chromosome 12q13.3-14.1 just within the IBD2 region and is a key transcription factor involved in interleukin (IL)-4 and IL-13-mediated Th2 response. The aim of the present study was to determine distribution of the STAT6 gene polymorphism in Chinese patients with ulcerative colitis. METHODS: The G2964A...
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