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Article

Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen.

BMC gastroenterology - 27 Oct 2006

Selig Lena, Sack Ulrich, Gaiser Sebastian, Klöppel Günter, Savkovic Vuk, Mössner Joachim, Keim Volker, Bödeker Hans

Abstract excerpt

BACKGROUND: The R122H mutation of the cationic trypsinogen was found in patients with hereditary pancreatitis. A transgenic animal carrying this mutation could be useful as a genetic model system of pancreatitis. METHODS: Mice transgenic for the human R122H cationic trypsinogen were generated usi...

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Identifiers

PMID: 17069643
DOI: 10.1186/1471-230X-6-30
PMCID: PMC1637108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17069643-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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